For research use only. Not for therapeutic Use.
Zapalog is a synthetic chemical tool used in optogenetics and cell signaling research. It is a photoconvertible dimerizer that enables precise, reversible control of protein-protein interactions within cells using light. By binding to specific proteins that have been engineered to interact with Zapalog, researchers can use light to trigger or disrupt these interactions in a controlled manner, allowing for the study of dynamic cellular processes in real-time. Zapalog is particularly valuable for investigating signaling pathways, cellular responses, and other complex biological mechanisms with high spatial and temporal resolution. Its application extends to various fields, including neuroscience, cell biology, and developmental biology.
| Catalog Number | I018093 |
| CAS Number | 1708091-24-0 |
| Synonyms | [(1R)-1-[3-[4-[4-[1-[2-[4-[(2,4-diaminopyrimidin-5-yl)methyl]-2,6-dimethoxyphenoxy]ethoxy]ethyl]-2-methoxy-5-nitrophenoxy]butanoylamino]phenyl]-3-(3,4-dimethoxyphenyl)propyl] (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate |
| Molecular Formula | C58H73N7O15 |
| Purity | ≥95% |
| IUPAC Name | [(1R)-1-[3-[4-[4-[1-[2-[4-[(2,4-diaminopyrimidin-5-yl)methyl]-2,6-dimethoxyphenoxy]ethoxy]ethyl]-2-methoxy-5-nitrophenoxy]butanoylamino]phenyl]-3-(3,4-dimethoxyphenyl)propyl] (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate |
| InChI | InChI=1S/C58H73N7O15/c1-10-58(3,4)53(67)55(68)64-23-12-11-17-42(64)56(69)80-44(21-19-36-20-22-45(72-5)46(28-36)73-6)38-15-13-16-40(31-38)62-51(66)18-14-24-78-48-33-43(65(70)71)41(32-47(48)74-7)35(2)77-25-26-79-52-49(75-8)29-37(30-50(52)76-9)27-39-34-61-57(60)63-54(39)59/h13,15-16,20,22,28-35,42,44H,10-12,14,17-19,21,23-27H2,1-9H3,(H,62,66)(H4,59,60,61,63)/t35?,42-,44+/m0/s1 |
| InChIKey | ONSMHWXTRWDIMR-SXIGHEGWSA-N |
| SMILES | CCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OC(CCC2=CC(=C(C=C2)OC)OC)C3=CC(=CC=C3)NC(=O)CCCOC4=C(C=C(C(=C4)[N+](=O)[O-])C(C)OCCOC5=C(C=C(C=C5OC)CC6=CN=C(N=C6N)N)OC)OC |
