For research use only. Not for therapeutic Use.
ZCAN262 (compound 6 ) is an AMPA modulator. ZCAN262 prevents AMPA-mediated excitotoxicity by targeting an allosteric binding site[1].
| Catalog Number | I040210 |
| Synonyms | 2-[2-[(2,4-difluorophenyl)methyl]-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-N,N-dimethylpyrimidine-4-carboxamide |
| Molecular Formula | C19H18F2N6O |
| Purity | ≥95% |
| InChI | InChI=1S/C19H18F2N6O/c1-25(2)18(28)16-5-6-22-19(23-16)26-8-13-10-27(24-17(13)11-26)9-12-3-4-14(20)7-15(12)21/h3-7,10H,8-9,11H2,1-2H3 |
| InChIKey | JYKQUGHLYOBLQZ-UHFFFAOYSA-N |
| SMILES | CN(C)C(=O)C1=NC(=NC=C1)N2CC3=CN(N=C3C2)CC4=C(C=C(C=C4)F)F |
| Reference | [1]. Dongxu Zhai, et al. Small-molecule targeting AMPA-mediated excitotoxicity has therapeutic effects in mouse models for multiple sclerosis. Sci Adv. 2023, 9, 49. |
