ZCZ011

For research use only. Not for therapeutic Use.

  • CAT Number: I010139
  • CAS Number: 1998197-39-9
  • Molecular Formula: C21H18N2O2S
  • Molecular Weight: 362.44
  • Purity: ≥95%
Inquiry Now

ZCZ011(Cat No.:I010139)is a small molecule inhibitor that targets the protein CENP-E (centromere protein E), a crucial motor protein involved in chromosome segregation during mitosis. By inhibiting CENP-E, ZCZ011 disrupts the proper alignment and separation of chromosomes, leading to mitotic arrest and potential cell death in rapidly dividing cancer cells. This mechanism makes ZCZ011 a promising candidate for cancer therapy, particularly for tumors with high proliferative activity. Preclinical studies suggest that ZCZ011 may offer a novel therapeutic strategy to target mitotic processes in cancer treatment.


CAS Number 1998197-39-9
Synonyms

6-methyl-3-(2-nitro-1-thiophen-2-ylethyl)-2-phenyl-1H-indole

Molecular Formula C21H18N2O2S
Purity ≥95%
IUPAC Name 6-methyl-3-(2-nitro-1-thiophen-2-ylethyl)-2-phenyl-1H-indole
InChI InChI=1S/C21H18N2O2S/c1-14-9-10-16-18(12-14)22-21(15-6-3-2-4-7-15)20(16)17(13-23(24)25)19-8-5-11-26-19/h2-12,17,22H,13H2,1H3
InChIKey RJSPNRDBWHHFMH-UHFFFAOYSA-N
SMILES CC1=CC2=C(C=C1)C(=C(N2)C3=CC=CC=C3)C(C[N+](=O)[O-])C4=CC=CS4
Chemistry Calculators Dilution Calculator
In vivo Formulation Calculator
Molarity Calculator
Molecular Weight Calculator
Reconstitution Calculator

Request a Quote