Zelminemab

• CAT Number: I042138
• CAS Number: 2225850-33-7
• Purity: ≥95%

Zelminemab (AMG-301) is a humanized monoclonal antibody that inhibits PACAP type I (PAC1) receptor[1].
Zelminemab (10 mg/kg; i.v.; once) reduces nociceptive neu-ronal activity in the TCC[2].

Reference

[1]. Eloisa Rubio-Beltrán, et al. PACAP38 and PAC1 receptor blockade: a new target for headache? J Headache Pain. 2018 Aug 7;19(1):64.
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[2]. Hoffmann J, et al. PAC-1 receptor antibody modulates nociceptive trigeminal activity in rat. Cephalalgia. 2016;36(1S):141–141.