ZG-10

• CAT Number: I038690
• CAS Number: 1408077-04-2
• Molecular Formula: C28H27N7O2
• Molecular Weight: 493.57
• Purity: 98%
• Synonyms: ZG-10; ZG 10; ZG10
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
• InChI: InChI=1S/C28H27N7O2/c1-35(2)17-5-9-26(36)31-22-12-10-20(11-13-22)27(37)32-23-7-3-8-24(18-23)33-28-30-16-14-25(34-28)21-6-4-15-29-19-21/h3-16,18-19H,17H2,1-2H3,(H,31,36)(H,32,37)(H,30,33,34)/b9-5+
• InChIKey: VZEONOGFXYTZGT-WEVVVXLNSA-N
• SMILES: CN(C)C/C=C/C(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=CC(=N3)C4=CN=CC=C4

ZG-10（Cat No.:I038690）is a small molecule compound that has been investigated for its potential neuroprotective and cognitive-enhancing effects. It acts primarily as a positive allosteric modulator of the α7 nicotinic acetylcholine receptor (nAChR), which plays a key role in learning, memory, and synaptic plasticity. By enhancing α7 nAChR activity, ZG-10 may improve cognitive functions and could be of interest for treating neurodegenerative diseases such as Alzheimer’s and other conditions associated with cognitive decline. Research into its efficacy and safety is ongoing, and its clinical application is still under exploration.