For research use only. Not for therapeutic Use.
Zidesamtinib (NVL-520) is a potent brain-penetrating inhibitor of ROS1 tyrosine kinase with IC50 of 0.7 nM for wild-type ROS1 . It acts as a potential antineoplastic agent and can be used for the research of cancer.
| Catalog Number | I047533 |
| CAS Number | 2739829-00-4 |
| Molecular Formula | C22H22FN7O |
| Purity | ≥95% |
| Reference | [1] Drilon A, et al. Cancer Discov. 2023 Mar 1;13(3):598-615. |
