For research use only. Not for therapeutic Use.
ZINC000006658090 is a potent, conformationally selective and non-competitive SERT inhibitor with a Ki value of 14 nM.
KEYWORDS: ZINC000006658090 | Supplier | SERT inhibitor | SERT inhibitor compound 8090 | ZINC-000006658090 | ZINC000006658090 | CAS [887625-25-4] | Serotonin | Inhibitor
| Catalog Number | I047718 |
| CAS Number | 887625-25-4 |
| Molecular Formula | C13H14FN3S |
| Purity | ≥95% |
| IUPAC Name | 4-(4-fluorophenyl)-2-piperazin-1-yl-1,3-thiazole |
| InChI | InChI=1S/C13H14FN3S/c14-11-3-1-10(2-4-11)12-9-18-13(16-12)17-7-5-15-6-8-17/h1-4,9,15H,5-8H2 |
| SMILES | C1CN(CCN1)C2=NC(=CS2)C3=CC=C(C=C3)F |
| Reference | I Singh et al. Structure-based discovery of conformationally selective inhibitors of the serotonin transporter. Cell. 2023 May 11;186(10):2160-2175. |
