For research use only, not for therapeutic use.
ZINC03129319（Cat No.:I020079） is an inhibitor of the dengue virus (DENV) NS2B-NS3 protease. It is extracted from a patent (US20150141521A1). This compound has demonstrated inhibition constants (Ki) of 92 μM (Ki1) and 20 μM (Ki3). The NS2B-NS3 protease is crucial for the replication of the dengue virus, and inhibiting its activity can impede viral replication. ZINC03129319 shows potential as a candidate for further development as an antiviral agent against dengue virus infection.
| Catalog Number | I020079 |
| CAS Number | 1777807-64-3 |
| Molecular Formula | C₂₄H₁₄N₂O₆S₂ |
| Purity | ≥95% |
| Storage | Store at -20°C |
| InChI | InChI=1S/C24H14N2O6S2/c27-17-11-5-1-2-6-12(11)18(28)23(17)25-15(9-33-23)22(32)26-16(21(25)31)10-34-24(26)19(29)13-7-3-4-8-14(13)20(24)30/h1-8,15-16H,9-10H2/t15-,16-/m1/s1 |
| InChIKey | GBYAWPJNMFAKDJ-HZPDHXFCSA-N |
| SMILES | C1C2C(=O)N3C(CSC34C(=O)C5=CC=CC=C5C4=O)C(=O)N2C6(S1)C(=O)C7=CC=CC=C7C6=O |
| Reference | [1]. Watowich, Stanley J, et al. SMALL-MOLECULE INHIBITORS OF DENGUE VIRUS PROTEASES. US20150141521A1. |
