For research use only. Not for therapeutic Use.
Ziprasidone HCl is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder.<br>Ziprasidone has high affinity for human 5-HT receptors and for human dopamine D(2) receptors. Ziprasidone is a 5-HT(1A) receptor agonist and an antagonist at 5-HT(2A), 5-HT(2C) and 5-HT(1B/1D) receptors. Ziprasidone inhibits neuronal uptake of 5-HT and norepinephrine comparable to the antidepressant imipramine.<br>Ziprasidone exhibits less potent block of wild-type hERG current with IC(50) of 2.8 mM in Xenopus oocytes.
| Catalog Number | A000798 |
| CAS Number | 122883-93-6 |
| Synonyms | CP-88059 |
| Molecular Formula | C21H21ClN4OS.HCl |
| Purity | ≥95% |
| Target | 5-HT Receptor |
| Solubility | Soluble in DMSO > 10 mM |
| Storage | 3 years -20C powder |
