Ziprasidone

• CAT Number: I010152
• CAS Number: 146939-27-7
• Molecular Formula: C21H21ClN4OS
• Molecular Weight: 412.94
• Purity: ≥95%
• Synonyms: CP88059; CP-88059; CP 88059; CP-88,059; CP-88,059-01; CP88059 hydrochloride; Ziprasidone HCl, brand name: Geodon; Zeldox; Zipwell.;5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one
• InChI: InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)
• InChIKey: MVWVFYHBGMAFLY-UHFFFAOYSA-N
• SMILES: C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54

Ziprasidone(CAT: I010152) is an atypical antipsychotic primarily used for the treatment of schizophrenia and bipolar disorder. It acts as a dopamine D2 receptor antagonist and a serotonin 5-HT2A receptor antagonist, with additional affinity for serotonin 5-HT1A, 5-HT1D, and norepinephrine reuptake transporters. This multi-receptor activity helps regulate neurotransmitter imbalances associated with psychotic and mood disorders. Ziprasidone is particularly valued in neuropsychiatric research for exploring dopaminergic and serotonergic pathways and their roles in mental health. Its relatively low risk of weight gain and metabolic side effects also makes it a focus of studies on optimizing antipsychotic therapy for improved patient outcomes.