ZK824190 hydrochloride

• CAT Number: I043926
• CAS Number: 2629177-12-2
• Molecular Formula: C22H21ClF2N2O4
• Molecular Weight: 450.86
• Purity: ≥95%
• Synonyms: (2R)-2-[6-[3-[3-(aminomethyl)phenyl]phenoxy]-3,5-difluoropyridin-2-yl]oxybutanoic acid;hydrochloride
• InChI: InChI=1S/C22H20F2N2O4.ClH/c1-2-19(22(27)28)30-21-18(24)11-17(23)20(26-21)29-16-8-4-7-15(10-16)14-6-3-5-13(9-14)12-25;/h3-11,19H,2,12,25H2,1H3,(H,27,28);1H/t19-;/m1./s1
• InChIKey: IXYNABONTFZVBF-FSRHSHDFSA-N
• SMILES: CC[C@H](C(=O)O)OC1=C(C=C(C(=N1)OC2=CC=CC(=C2)C3=CC=CC(=C3)CN)F)F.Cl

ZK824190 hydrochloride（Cat No.:I043926）is a potent and selective small molecule inhibitor of the GPR40 receptor (also known as FFAR1), a G-protein coupled receptor involved in regulating insulin secretion and glucose metabolism. By targeting GPR40, ZK824190 hydrochloride enhances glucose-dependent insulin release, making it a promising therapeutic candidate for type 2 diabetes and other metabolic disorders. This compound has shown efficacy in preclinical models, offering potential benefits in managing blood sugar levels by modulating insulin secretion. ZK824190 hydrochloride’s ability to target GPR40 offers a novel approach in diabetes treatment.