For research use only. Not for therapeutic Use.
ZLD115 (compound 44) is a FB23-derivated inhibitor of Fat Mass and Obesity-associated Protein (FTO). ZLD115 is an antileukemic agent, exhibiting antiproliferative activity against leukemic cell lines[1].
| Catalog Number | I041006 |
| CAS Number | 2980653-93-6 |
| Synonyms | 2-[2-chloro-6-cyclopropyl-4-(3,5-dimethyl-1,2-oxazol-4-yl)anilino]-6-(1,4-oxazepan-4-ylmethyl)benzoic acid |
| Molecular Formula | C27H30ClN3O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C27H30ClN3O4/c1-16-24(17(2)35-30-16)20-13-21(18-7-8-18)26(22(28)14-20)29-23-6-3-5-19(25(23)27(32)33)15-31-9-4-11-34-12-10-31/h3,5-6,13-14,18,29H,4,7-12,15H2,1-2H3,(H,32,33) |
| InChIKey | INIIJQVYGFIRNI-UHFFFAOYSA-N |
| SMILES | CC1=C(C(=NO1)C)C2=CC(=C(C(=C2)Cl)NC3=CC=CC(=C3C(=O)O)CN4CCCOCC4)C5CC5 |
| Reference | [1]. Xiao P, et al. Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties. J Med Chem. 2023 Jul 7. |
