For research use only. Not for therapeutic Use.
Zofenopril (Cat.No:I013170) is an angiotensin-converting enzyme (ACE) inhibitor commonly used in cardiovascular medicine. It helps manage hypertension and congestive heart failure by lowering blood pressure and reducing strain on the heart. Zofenopril’s efficacy, tolerability, and proven clinical benefits have made it a valuable option in cardiovascular treatment.
| Catalog Number | I013170 |
| CAS Number | 81872-10-8 |
| Molecular Formula | C₂₂H₂₃NO₄S₂ |
| Purity | ≥95% |
| Target | Angiotensin-converting Enzyme (ACE) |
| Solubility | DMSO: 5 mg/mL (Need ultrasonic) |
| IUPAC Name | (2S,4S)-1-[(2S)-3-benzoylsulfanyl-2-methylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylic acid |
| InChI | InChI=1S/C22H23NO4S2/c1-15(14-28-22(27)16-8-4-2-5-9-16)20(24)23-13-18(12-19(23)21(25)26)29-17-10-6-3-7-11-17/h2-11,15,18-19H,12-14H2,1H3,(H,25,26)/t15-,18+,19+/m1/s1 |
| InChIKey | IAIDUHCBNLFXEF-MNEFBYGVSA-N |
| SMILES | CC(CSC(=O)C1=CC=CC=C1)C(=O)N2CC(CC2C(=O)O)SC3=CC=CC=C3 |
| Reference | [1]. Lin CJ, et al. Competitive inhibition of glycylsarcosine transport by enalapril in rabbit renal brush border membrane vesicles: interaction of ACE inhibitors with high-affinity H+/peptide symporter. Pharm Res. 1999 May;16(5):609-15.<br>[2]. Sarro GD, et al. Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice. Pharmacol Res. 2012 Mar;65(3):285-96. |
