Zoloperone

• CAT Number: I038770
• CAS Number: 52867-74-0
• Molecular Formula: C22H24FN3O3
• Molecular Weight: 397.45
• Purity: 98%
• Synonyms: Zoloperone; LR 511; LR-511; LR511; Zoloperonum
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 4-(4-fluorophenyl)-5-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)oxazol-2(3H)-one
• InChI: InChI=1S/C22H24FN3O3/c1-28-19-5-3-2-4-18(19)26-14-12-25(13-15-26)11-10-20-21(24-22(27)29-20)16-6-8-17(23)9-7-16/h2-9H,10-15H2,1H3,(H,24,27)
• InChIKey: FCMGKQUKZIJJSH-UHFFFAOYSA-N
• SMILES: O=C1OC(CCN2CCN(C3=CC=CC=C3OC)CC2)=C(C4=CC=C(F)C=C4)N1

Zoloperone(CAT: I038770) is a potent and selective dopamine D2 receptor antagonist, widely used in neuropharmacology research to study dopaminergic pathways and their role in psychiatric and neurological disorders. By blocking dopamine D2 receptors, Zoloperone modulates dopaminergic neurotransmission, making it a valuable tool for investigating conditions such as schizophrenia, bipolar disorder, and Parkinson’s disease. Its high affinity for D2 receptors also makes it useful in receptor binding assays and studies on drug-receptor interactions. Zoloperone provides critical insights into the development of antipsychotic drugs and therapies targeting dopamine-related dysfunctions in the central nervous system.