ZXH-1-161

For research use only. Not for therapeutic Use.

  • CAT Number: I038693
  • CAS Number: 2407654-51-5
  • Molecular Formula: C26H24N6O3
  • Molecular Weight: 468.51
  • Purity: ≥95%
Inquiry Now

ZXH-1-161(Cat No.:I038693)is a selective small-molecule inhibitor targeting the STAT3 (Signal Transducer and Activator of Transcription 3) signaling pathway, which plays a pivotal role in cancer progression, inflammation, and immune regulation. By blocking STAT3 phosphorylation and dimerization, ZXH-1-161 inhibits its nuclear translocation and transcriptional activity, leading to the suppression of oncogenic gene expression. This compound has shown promising anticancer effects by inducing apoptosis and inhibiting tumor cell proliferation. ZXH-1-161 is also a valuable tool for studying STAT3-driven mechanisms and holds therapeutic potential for treating STAT3-dependent cancers and inflammatory diseases.


CAS Number 2407654-51-5
Synonyms

3-[7-[[2-(2,3-dihydro-1H-inden-5-ylamino)pyrimidin-4-yl]amino]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione

Molecular Formula C26H24N6O3
Purity ≥95%
IUPAC Name 3-[7-[[2-(2,3-dihydro-1H-inden-5-ylamino)pyrimidin-4-yl]amino]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
InChI InChI=1S/C26H24N6O3/c33-23-10-9-21(24(34)31-23)32-14-19-18(25(32)35)5-2-6-20(19)29-22-11-12-27-26(30-22)28-17-8-7-15-3-1-4-16(15)13-17/h2,5-8,11-13,21H,1,3-4,9-10,14H2,(H,31,33,34)(H2,27,28,29,30)
InChIKey KCIIVRZRNLZKQA-UHFFFAOYSA-N
SMILES C1CC2=C(C1)C=C(C=C2)NC3=NC=CC(=N3)NC4=CC=CC5=C4CN(C5=O)C6CCC(=O)NC6=O
Chemistry Calculators Dilution Calculator
In vivo Formulation Calculator
Molarity Calculator
Molecular Weight Calculator
Reconstitution Calculator

Request a Quote