For research use only. Not for therapeutic Use.
ZY-1(CAT: I040984) is a non-fluorescent control molecule for ZY-2 (HY-D1876), a PKM2 fluorescent probe, designed for cancer metabolism and glycolysis research. It exhibits low fluorescence emission in HeLa cells, which are known for their high pyruvate kinase M2 (PKM2) expression. ZY-1 serves as a negative control in fluorescence-based PKM2 detection assays, ensuring specificity in experimental studies. This compound is valuable for validating PKM2-selective imaging and studying cancer cell metabolic regulation. Suitable for biochemical, cellular, and fluorescence-based applications. For research use only; not for human or clinical applications.
Catalog Number | I040984 |
Synonyms | 2-[4-[4-[(E)-2-(1-ethylpyridin-1-ium-4-yl)ethenyl]phenyl]piperazin-1-yl]acetic acid;2,2,2-trifluoroacetate |
Molecular Formula | C23H26F3N3O4 |
Purity | ≥95% |
IUPAC Name | 2-[4-[4-[(E)-2-(1-ethylpyridin-1-ium-4-yl)ethenyl]phenyl]piperazin-1-yl]acetic acid;2,2,2-trifluoroacetate |
InChI | InChI=1S/C21H25N3O2.C2HF3O2/c1-2-22-11-9-19(10-12-22)4-3-18-5-7-20(8-6-18)24-15-13-23(14-16-24)17-21(25)26;3-2(4,5)1(6)7/h3-12H,2,13-17H2,1H3;(H,6,7) |
InChIKey | NSWNWEHWKWXTPU-UHFFFAOYSA-N |
SMILES | CC[N+]1=CC=C(C=C1)C=CC2=CC=C(C=C2)N3CCN(CC3)CC(=O)O.C(=O)(C(F)(F)F)[O-] |