For research use only. Not for therapeutic Use.
ZY-444 is a small molecule that suppresses breast cancer progression by targeting pyruvate carboxylase.
| Catalog Number | I045204 |
| CAS Number | 1802650-31-2 |
| Synonyms | 2-N-(2-methylpropyl)-4-N-[[5-(4-phenylmethoxyphenyl)thiophen-2-yl]methyl]pyrimidine-2,4-diamine |
| Molecular Formula | C26H28N4OS |
| Purity | ≥95% |
| InChI | InChI=1S/C26H28N4OS/c1-19(2)16-29-26-27-15-14-25(30-26)28-17-23-12-13-24(32-23)21-8-10-22(11-9-21)31-18-20-6-4-3-5-7-20/h3-15,19H,16-18H2,1-2H3,(H2,27,28,29,30) |
| InChIKey | ROSPRUQNDJIWDD-UHFFFAOYSA-N |
| SMILES | CC(C)CNC1=NC=CC(=N1)NCC2=CC=C(S2)C3=CC=C(C=C3)OCC4=CC=CC=C4 |
| Reference | [1]. Lin Q, et al. Targeting Pyruvate Carboxylase by a Small Molecule Suppresses Breast Cancer Progression. Adv Sci (Weinh). 2020 Mar 12;7(9):1903483. |
