Zymosan A

• CAT Number: R001549
• CAS Number: 58856-93-2
• Purity: ≥95%

Zymosan A (Zymosan A from Saccharomyces cerevisiae) is a TLR2 agonist, that targeting TLRs can prevent and suppress IR-induced intestinal injury. Zymosan A exhibits a significant radioprotective effect, and protects IR-induced intestinal injury in mice. Zymosan A promotes the regeneration of intestinal stem cells (ISCs), after IR injury[1].
Zymosan A can be used in animal modeling to establish a mouse peritonitis model.Zymosan A (25.0 mg/kg; IP at 12 and 2 h before IR) mitigates IR-induced intestinal injury in mice[1].

Reference

[1]. Du J, et al. Zymosan-A promotes the regeneration of intestinal stem cells by upregulating ASCL2. Cell Death Dis. 2022 Oct 20;13(10):884.
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