This protein kinase transduces mitogenic signals from the cell membrane to the nucleus, likely playing a critical role in cellular signaling. It phosphorylates MAP2K1, activating the MAP kinase signaling pathway, which regulates various processes such as cell proliferation and differentiation. Additionally, it phosphorylates PFKFB2, suggesting a role in metabolic regulation. In the nervous system, this kinase may contribute to postsynaptic responses in hippocampal neurons, potentially influencing synaptic plasticity and neural communication. Its dual roles in signal transduction and neural function highlight its importance in both cellular and neurological processes.
Product Name | Recombinant Human BRAF Protein |
Accession | P15056 |
Host Species | Human |
Gene | BRAF |
Source | Sf9 |