This protein anchors the extracellular matrix to the cytoskeleton by interacting with F-actin and serves as a ligand for dystroglycan. It is a key component of the dystrophin-associated glycoprotein complex, which accumulates at the neuromuscular junction (NMJ) and various synapses in the peripheral and central nervous systems. This complex plays a critical structural role in stabilizing the sarcolemma, ensuring the integrity of muscle fibers during contraction. Beyond its structural function, the protein is also involved in signaling pathways and synaptic transmission, contributing to communication and connectivity within the nervous system. Its dual roles in stabilization and signaling highlight its importance in maintaining muscle and neural function.
| Product Name | Recombinant Human Dystrophin Protein (Tagged) |
| Accession | P11532 |
| Host Species | Human |
| Gene | DMD |
| Source | Wheat germ |
