The receptor for sphingosine 1-phosphate (S1P), a bioactive lysophospholipid, mediates diverse physiological effects across various cell types and tissues. This receptor is coupled to both G(i/0)alpha and G12 subclasses of heteromeric G-proteins, facilitating signal transduction (by similarity). It may play a critical role in the transformation of radial glial cells into astrocytes, influencing their proliferative activity. Through its interaction with S1P, the receptor regulates cellular responses crucial for development, proliferation, and differentiation, highlighting its importance in maintaining tissue homeostasis and promoting cell-type-specific functions during physiological and developmental processes.
| Product Name | Recombinant Human EDG8 Protein |
| Accession | Q9H228 |
| Host Species | Human |
| Gene | S1PR5 |
| Source | Wheat germ |
