This receptor is the beta subunit for interleukin-2 (IL-2) and plays a crucial role in receptor-mediated endocytosis, transducing IL-2’s mitogenic signals. It is likely involved in the stimulation of neutrophil phagocytosis by IL-15, in association with IL-15RA. The beta subunit is essential for IL-2 receptor signaling and participates in immune cell activation and proliferation. Through its interaction with IL-15RA, it contributes to enhancing the immune response, particularly in neutrophil function, playing an important role in the body’s defense mechanisms.
Product Name | Recombinant Human Interleukin-2 receptor subunit beta (IL2RB),partial |
Accession | P14784 |
Purity | >85% (SDS-PAGE) |
Host Species | Homo sapiens (Human) |
Gene | IL2RB |
Source | E.coli;In Vivo Biotinylation in E.coli;Yeast;Baculovirus;Mammalian cell |
Tag | Tag type will be determined during the manufacturing process. |
Form | Lyophilized powder |
Buffer | Tris/PBS-based buffer, 6% Trehalose. |
Storage | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Protein Length | Partial |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Shelf Life | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature |
Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |