Recombinant Human Melanocortin receptor 4 (MC4R), partial

• Purity: >85% (SDS-PAGE)
• Host Species: Homo sapiens (Human)
• Accession: P32245
• Gene: MC4R
• CAT.NO: B000275
• Expression Systems: Yeast E.coli Baculovirus Mammalian cell
• Product Name: Recombinant Human Melanocortin receptor 4 (MC4R), partial
• Source: Yeast;E.coli;Baculovirus;Mammalian cell
• Tag: Tag type will be determined during the manufacturing process.
• Form: Lyophilized powder
• Buffer: Tris/PBS-based buffer, 6% Trehalose.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Alternative Names: MC4R; Melanocortin receptor 4; MC4-R
• Protein Length: Partial
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Shelf Life: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.; Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

This receptor is specific to the heptapeptide core shared by adrenocorticotropic hormone (ACTH) and alpha-, beta-, and gamma-MSH. It plays a central role in regulating energy homeostasis and somatic growth. The receptor is activated by G proteins, which stimulate adenylate cyclase to produce cyclic AMP (cAMP) as a second messenger. Through this signaling pathway, it influences various physiological processes, including metabolism, stress response, and growth. Its activation helps coordinate the body’s response to hormonal signals related to energy balance and growth regulation.