Recombinant Human Molybdopterin Synthase Catalytic Subunit (MOCS2) Protein (GST)

• Purity: Greater than 90% as determined by SDS-PAGE.
• Host Species: Human
• Accession: O96007
• Gene: MOCS2
• CAT.NO: B000104
• Expression Systems: E.coli
• Product Name: Recombinant Human Molybdopterin Synthase Catalytic Subunit (MOCS2) Protein (GST)
• Protein Expression Range: 1-188aa
• Tag: N-GST
• Molecular Mass: 47.9kDa
• Form: Liquid or Lyophilized powder
• Buffer: Liquid form: default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Storage: 1. Store at -20¡«C/-80¡«C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4¡«C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20¡«C/-80¡«C. Protein in lyophilized powder form is stable for up to 12 months at -20¡«C/-80¡«C.

This protein serves as the catalytic subunit of the molybdopterin synthase complex, which is essential for converting precursor Z into molybdopterin. It facilitates the incorporation of two sulfur atoms from the thiocarboxylated MOCS2A subunit into precursor Z, resulting in the formation of a dithiolene group. This reaction is a critical step in the biosynthesis of molybdopterin, a cofactor required for the activity of various molybdoenzymes. The process ensures the proper functioning of metabolic pathways dependent on molybdenum-containing enzymes.