Myosins are actin-based motor proteins with ATPase activity, essential for muscle contraction. They assemble into regular bipolar thick filaments, which interact with actin thin filaments to form the fundamental contractile units of skeletal and cardiac muscle. These thick filaments generate force and facilitate movement by converting chemical energy from ATP hydrolysis into mechanical work. Myosins play a central role in the sliding filament mechanism, driving the contraction and relaxation cycles necessary for muscle function. Their precise structural organization and dynamic interaction with actin are critical for maintaining muscle performance and supporting vital physiological processes such as locomotion and cardiac activity.
| Product Name | Recombinant Human Myosin-7 (MYH7) Protein (His) |
| Accession | P12883 |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Host Species | Human |
| Gene | MYH7 |
| Source | E.coli |
| Protein Expression Range | 1-109aa |
| Tag | N-10His |
| Molecular Mass | 18.5 kDa |
| Form | Liquid or Lyophilized powder |
| Buffer | Liquid form: default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
| Storage | 1. Store at -20¡«C/-80¡«C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4¡«C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20¡«C/-80¡«C. Protein in lyophilized powder form is stable for up to 12 months at -20¡«C/-80¡«C. |
