Recombinant Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (NDUFA13)

• Purity: >85% (SDS-PAGE)
• Host Species: Homo sapiens (Human)
• Accession: Q9P0J0
• Gene: NDUFA13
• CAT.NO: B000245
• Expression Systems: E.coli In Vivo Biotinylation in E.coli Yeast Baculovirus Mammalian cell
• Product Name: Recombinant Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (NDUFA13)
• Source: E.coli;In Vivo Biotinylation in E.coli;Yeast;Baculovirus;Mammalian cell
• Tag: Tag type will be determined during the manufacturing process.
• Form: Lyophilized powder
• Buffer: Tris/PBS-based buffer, 6% Trehalose.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Protein Length: Partial
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Shelf Life: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature; and the stability of the protein itself.; Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized; form is 12 months at -20°C/-80°C.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

This accessory subunit is part of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) and is not believed to be directly involved in catalysis. Complex I transfers electrons from NADH to the respiratory chain, with ubiquinone acting as the immediate electron acceptor. It is implicated in interferon/all-trans-retinoic acid (IFN/RA)-induced cell death, an apoptotic process inhibited by interaction with viral IRF1, which prevents the transactivation of STAT3 target genes. Additionally, it may play a role in CARD15-mediated innate mucosal responses and regulate intestinal epithelial cell responses to microbes.