Recombinant Human Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD), partial

• Purity: >85% (SDS-PAGE)
• Host Species: Homo sapiens (Human)
• Accession: O00329
• Gene: PIK3CD
• CAT.NO: B000139
• Expression Systems: E.coli In Vivo Biotinylation in E.coli Yeast Baculovirus Mammalian cell
• Product Name: Recombinant Human Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD), partial
• Source: E.coli;In Vivo Biotinylation in E.coli;Yeast;Baculovirus;Mammalian cell
• Tag: Tag type will be determined during the manufacturing process.
• Form: Lyophilized powder
• Buffer: Tris/PBS-based buffer, 6% Trehalose.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Alternative Names: 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; 5-bisphosphate 3-kinase catalytic subunit delta isoform; APDS; GRB1; IMD14; p110d; p110delta; p110dp85a; p85-ALPHA ; Phosphatidylinositol 3 kinase catalytic delta polypeptide; Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform; Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit delta; Phosphatidylinositol 4,5 bisphosphate 3 kinase; catalytic subunit delta; Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit delta isoform; Phosphatidylinositol-4; Phosphoinositide 3 kinase B; Phosphoinositide 3 kinase C; Phosphoinositide 3 kinase catalytic delta polypeptide; Phosphoinositide 3 kinase; catalytic; delta polypeptide variant p37delta; PI3 kinase p110 subunit delta; PI3-kinase subunit delta; PI3K; PI3K-delta; PI3Kdelta; Pik3cd; PIK3R1; PK3CD; PK3CD_HUMAN; PtdIns 3 kinase p110; PtdIns 3 kinase subunit p110 delta; PtdIns-3-kinase subunit delta; PtdIns-3-kinase subunit p110-delta
• Protein Length: Partial
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Shelf Life: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.; Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Phosphoinositide-3-kinase (PI3K) catalyzes the phosphorylation of phosphatidylinositol (PI) and its phosphorylated derivatives at the 3-position of the inositol ring, generating 3-phosphoinositides. It utilizes ATP and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) as substrates to produce phosphatidylinositol 3,4,5-trisphosphate (PIP3). This reaction is critical for the regulation of various cellular processes, including cell growth, survival, and metabolism. PIP3 acts as a signaling molecule, recruiting and activating proteins involved in signal transduction pathways that regulate processes such as cell proliferation, migration, and differentiation.