This receptor binds prostaglandin E2 (PGE2) and mediates its effects through G(s) proteins, which activate adenylate cyclase. The resulting increase in intracellular cAMP leads to smooth muscle relaxation. By facilitating this signaling pathway, the receptor plays a key role in modulating physiological processes such as inflammation, vascular tone, and gastrointestinal motility, highlighting its importance in maintaining homeostasis and responding to external stimuli.
Product Name | Recombinant Human Prostaglandin E Receptor EP2/PTGER2 Protein |
Accession | P43116 |
Host Species | Human |
Gene | PTGER2 |
Source | Wheat germ |