Recombinant Human Sodium/hydrogen exchanger 3 (SLC9A3), partial

• Purity: >85% (SDS-PAGE)
• Host Species: Homo sapiens (Human)
• Accession: P48764
• Gene: SLC9A3
• CAT.NO: B000115
• Expression Systems: E.coli In Vivo Biotinylation in E.coli Yeast Baculovirus Mammalian cell
• Product Name: Recombinant Human Sodium/hydrogen exchanger 3 (SLC9A3), partial
• Source: E.coli;In Vivo Biotinylation in E.coli;Yeast;Baculovirus;Mammalian cell
• Tag: Tag type will be determined during the manufacturing process.
• Form: Lyophilized powder
• Buffer: Tris/PBS-based buffer, 6% Trehalose.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Alternative Names: MGC126718; MGC126720; Na(+)/H(+) exchanger 3; NHE 3; NHE-3; NHE3; SL9A3_HUMAN; SLC9A 3; Slc9a3; Sodium / Hydrogen Exchanger 3; Sodium/hydrogen exchanger 3; Sodium/hydrogen exchanger, apical epithelial; Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3; Solute carrier family 9 (sodium/hydrogen exchanger), member 3; Solute carrier family 9 member 3
• Protein Length: Partial
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Shelf Life: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.; Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

The plasma membrane Na+/H+ antiporter exchanges intracellular H+ ions for extracellular Na+ ions in a 1:1 ratio, playing a vital role in maintaining salt and fluid balance, as well as pH homeostasis. Recombinant Human Sodium/hydrogen exchanger 3 (SLC9A3), partial is the primary apical Na+/H+ exchanger in the kidney and intestine, where it significantly contributes to sodium absorption. In the kidney, this exchanger helps regulate sodium balance, while in the intestine, it facilitates efficient nutrient absorption. By controlling sodium levels, it also plays an essential role in blood pressure regulation, supporting overall fluid and electrolyte homeostasis in the body.