A thyroid hormone-binding protein, likely involved in transporting thyroxine (T4) from the bloodstream to the brain. It plays a crucial role in facilitating thyroid hormone distribution, ensuring proper hormonal regulation and availability for critical physiological processes, particularly in the central nervous system.
| Product Name | Recombinant Human Transthyretin (TTR) Protein (Fc-Myc), Active |
| Accession | P02766 |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Endotoxin | Less than 1.0 EU/ug as determined by LAL method. |
| Host Species | Human |
| Gene | TTR |
| Source | Mammalian cell |
| Protein Expression Range | 21-147aa |
| Tag | C-FC-Myc |
| Molecular Mass | 43.9 kDa |
| Form | Lyophilized powder |
| Buffer | Liquid form: default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
| Storage | 1. Store at -20¡«C/-80¡«C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4¡«C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20¡«C/-80¡«C. Protein in lyophilized powder form is stable for up to 12 months at -20¡«C/-80¡«C. |
| Bioactivity | Measured by its binding ability in a functional ELISA. Immobilized RBP4 at 5 μg/ml can bind human TTR, the EC 50 of human TTR protein is 284.7-391.7 ng/ml. |
