Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 4 (TNFRSF4) Protein (hFc), Active

• Purity: Greater than 95% as determined by SDS-PAGE.
• Host Species: Mus musculus (Mouse)
• Accession: P47741
• Gene: TNFRSF4
• CAT.NO: B000249
• Expression Systems: Mammalian cell
• Product Name: Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 4 (TNFRSF4) Protein (hFc), Active
• Endotoxin: Less than 1.0 EU/μg as determined by LAL method.
• Protein Expression Range: 20-211aa
• Tag: C-hFc
• Molecular Mass: 48.1 kDa
• Form: Lyophilized powder
• Buffer: Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4
• Storage: 1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.; 2. Avoid repeated freeze-thaw cycles.; 3. Store working aliquots at 4°C for up to one week.; 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C.
• Bioactivity: The ED50 as determined by its ability to bind Mouse TNFSF4 in functional ELISA is less than 2 ug/ml.
• Research Area: Cancer
• Protein Length: Extracellular Domain

The receptor for TNFSF4/OX40L/GP34 is a costimulatory molecule involved in the regulation of long-term T-cell immunity. It plays a critical role in enhancing T-cell activation and survival, contributing to the persistence of immune responses. This receptor is essential for the maintenance of immune memory, helping to sustain T-cell responses over time. Through its interaction with TNFSF4/OX40L, it supports immune system functions, making it an important player in the regulation of adaptive immune responses and immune tolerance.