Recombinant Variola Virus Envelope Protein F13 (C17L) Protein (His&Myc)

• Purity: Greater than 90% as determined by SDS-PAGE.
• Host Species: Variola virus
• Accession: P33815
• Gene: C17L
• CAT.NO: B000039
• Expression Systems: E.coli
• Product Name: Recombinant Variola Virus Envelope Protein F13 (C17L) Protein (His&Myc)
• Protein Expression Range: 1-372aa
• Tag: N-10His&C-Myc
• Molecular Mass: 49.4 kDa
• Form: Liquid or Lyophilized powder
• Buffer: Liquid form: default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Storage: 1. Store at -20¡«C/-80¡«C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4¡«C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20¡«C/-80¡«C. Protein in lyophilized powder form is stable for up to 12 months at -20¡«C/-80¡«C.

The major envelope protein is crucial for the biogenesis of the viral double membrane and facilitates the egress of the virus from the host cell. It produces the wrapped form of the virus, essential for efficient cell-to-cell transmission. This multifunctional protein also exhibits broad lipase activity, including phospholipase C, phospholipase A, and triacylglycerol lipase activities, contributing to lipid remodeling processes required for viral replication and spread. By integrating structural and enzymatic functions, this protein ensures the formation of infectious viral particles and their dissemination, making it a key player in the viral lifecycle and a potential target for antiviral strategies.